Volume 2.24 | Jun 22

Mesenchymal Cell News 2.24, June 22, 2010.
In this issue: Science News  |  Current Publications  |  Industry News  |  Policy News  |  Events Subscribe  |  Unsubscribe

TOP STORY

Adipose Tissue-Derived Mesenchymal Stem Cells Facilitate Hematopoiesis In Vitro and In Vivo. Advantages Over Bone Marrow-Derived Mesenchymal Stem Cells
In this study, researchers extensively evaluated the hematopoiesis-supporting properties of adipose tissue-derived mesenchymal stem cells, which are largely unknown. [Am J Pathol]

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SCIENCE NEWS

Stem Cells from Fat May Help Heal Bone in Wounded Soldiers
UC Davis biomedical engineer Kent Leach has received a CDMRP Hypothesis Development Award from the U.S. Army to explore a new approach to tissue regeneration that may speed bone healing and return to function. Dr. Leach will use stem cells derived from human adipose tissue to stimulate the formation of microvascular networks within developing bone. [PhysOrg Press Release]

STEMSOFTStemLab_645x110_gif


CURRENT PUBLICATIONS (Ranked by Impact Factor of the Journal)

Hypoxia Preconditioned Mesenchymal Stem Cells Improve Vascular and Skeletal Muscle Fiber Regeneration After Ischemia Through a Wnt4-dependent Pathway
Researchers investigated the ability of mesenchymal stem cells, exposed to short-term hypoxic conditions, to participate in vascular and tissue regeneration in an in vivo model of hindlimb ischemia. [Mol Ther]

A Differentiation-Based MicroRNA Signature Identifies Leiomyosarcoma as a Mesenchymal Stem Cell-Related Malignancy
Here, researchers demonstrated that microRNAs are required for full smooth muscle cell differentiation of bone marrow-derived human mesenchymal stem cells. [Am J Pathol]

Mesenchymal Stem Cells, Used As Bait, Disclose Tissue Binding Sites. A Tool in the Search for the Niche?
Researchers developed an ex vivo approach characterizing renal mesenchymal stem cell adhesion to kidney sections. [Am J Pathol]

Allogeneic Human Mesenchymal Stem Cells Restore Epithelial Protein Permeability in Cultured Human Alveolar Type II Cells by Secretion of Angiopoietin-1
Here, researchers tested the ability of human allogeneic mesenchymal stem cells to restore epithelial permeability to protein across primary cultures of polarized human alveolar epithelial type II cells following an inflammatory insult. [J Biol Chem]

Isolation of Adipose-Derived Stem Cells and Their Induction to a Chondrogenic Phenotype
Adipose-derived stem cells (ASCs) provide an abundant and easily accessible source of adult stem cells for use in regenerative approaches. This protocol first describes the isolation of ASCs from liposuction aspirate. [Nat Protoc]

Effects of the Architecture of Tissue Engineering Scaffolds on Cell Seeding and Culturing
Researchers assessed the influence of scaffold pore architecture on immortalised mesenchymal stem cell seeding and static culturing, by comparing a computer-designed gyroid architecture fabricated by stereolithography to a random-pore architecture resulting from salt-leaching. [Acta Biomater]

LIGHT (TNFSF14) Inhibits Adipose Differentiation Without Affecting Adipocyte Metabolism
LIGHT, a member of the tumor necrosis factor family, is a novel inhibitor of human adipocyte differentiation without adversely influencing central metabolic pathways in adipocytes. [Int J Obes]

Function Analysis of Mesenchymal Bcor in Tooth Development by Using RNA Interference
In this study, the Bcor expression pattern has been intensively investigated during mouse molar development. [Cell Tissue Res]


INDUSTRY NEWS

Breast Cancer Reconstruction Using Cell-Enriched Fat Grafts Shows Continued High Rates of Physician and Patient Satisfaction at Twelve Months
Interim results from a breast reconstruction trial show stem and regenerative cell-enriched fat grafting resulted in a high sustained rate of physician and patient satisfaction and persistent improvements in overall outcomes of the procedure at six and twelve months. [Cytori Therapeutics, Inc. Press Release]

Therapure Biopharma Inc. signs Biomanufacturing contract with ProChon Biotech Ltd.
Under the terms of the agreement, Therapure will provide services to support clinical manufacturing for one of ProChon’s products, which may be used for articular cartilage regeneration. [Therapure Biopharma Inc. Press Release]

BioLife Opens First StemSource® Cell Bank in U.S.
BioLife Cell Bank, LLC has opened the first U.S. StemSource® Cell Bank, which offers patients a way to safely and affordably store their own adipose tissue or their own naturally occurring adipose tissue-derived stem and regenerative cells. [BusinessWire]

UW Wins $12.6 Million Stem Cell Research Grant
Researchers at the University of Washington (UW), in Seattle, have received a $12.6 million federal grant to study how stem cells could help repair cardiovascular damage. [Pudget Sound Business Journal]


POLICY NEWS

Hospital Clinic de Barcelona Obtained the First Accreditation for Cell Therapy Research
The certification, awarded for the first time in Catalonia, allows the Hospital Clinic de Barcelona to produce drugs in gene therapy, cell therapy and tissue engineering. [Spanish Medicines Agency, Spain]

New Videos Reveal How NIH Identifies the Most Promising Research Applications
The National Institutes of Health’s Center for Scientific Review released a new video to show new applicants and others how NIH assesses over 80,000 grant applications each year to help find those with the most merit. [National Institutes of Health, United States]

Publication of New Enforcement Strategy
A new enforcement strategy has been published by the Inspection, Enforcement and Standards Division. [Medicines and Healthcare Products Regulatory Agency, United Kingdom]

Drugs Designated as Orphan Drugs
[Therapeutic Goods Administration, Australia]

Therapeutic Goods Committee (TGC) (Updated)
[Therapeutic Goods Administration, Australia]


EVENTS

Worldwide Innovative Networking (WIN) Symposium in Personalized Cancer Medicine
July 7-9, 2010
Paris, France

Translational Cancer Medicine 2010 – USA
July 11-14, 2010
San Francisco, United State

2nd International Conference on Cellular and Molecular Bioengineering (ICCMB2)
August 2-4, 2010
Singapore City, Singapore

Select Biosciences 3rd Annual Stem Cells Europe Conference
August 24-25, 2010
Edinburgh, Scotland

Select Biosciences Inaugural Cellular Therapy Summit
August 24-25, 2010
Edinburgh, Scotland


United Kingdom National Stem Cell Network (UKNSCN) 3rd Annual Scientific Conference
July 12-14, 2010
Nottingham, United Kingdom

Tissue Engineering & Regenerative Medicine International Society (TERMIS) – Asia Pacific 2010
September 15-17, 2010
Sydney, Australia

5th World Congress on Preventative and Regenerative Medicine (WCRM) 2010
October 5-7, 2010
Hannover, Germany

2010 American Society for Matrix Biology (ASMB) Meeting
October 24-27, 2010
Charleston, United States

52nd American Society of Hematology (ASH) Annual Meeting and Exposition
December 4-7, 2010
Orlando, United States

Tissue Engineering & Regenerative Medicine International Society (TERMIS) – North America 2010 Annual Conference
December 5-8, 2010
Orlando, United States

Visit our events page to stay up to date with the latest events in the cell, gene and immunotherapy community.

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