Volume 2.26 | Jul 6

Mesenchymal Cell News 2.26, July 6, 2010.
In this issue: Science News  |  Current Publications  |  Industry News  |  Policy News  |  Events Subscribe  |  Unsubscribe

TOP STORY

Stem Cells From Fat May Help Heal Bone 
Wounded soldiers may one day be treated with stem cells from their own fat using a method under development. [University of California, Davis Press Release]

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SCIENCE NEWS

Stem Cell Therapy May Provide New Approach to Fight Infection
A new study suggests that a commonly used type of bone marrow stem cell may be able to help treat sepsis. [Press release from the Ottawa Hospital Research Institute discussing online prepublication in the American Journal of Respiratory and Critical Care Medicine]

Utah Company Looks At Gels To Build Tissue
A Utah company has created a gel that allows cells to be injected into any site on the body, offering a way to regenerate tissue without grafts or transplants. [International Business Times Press Release]

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CURRENT PUBLICATIONS (Ranked by Impact Factor of the Journal)

Induction of Pluripotent Stem Cells from Human Third Molar Mesenchymal Stromal Cells
Researchers generated induced pluripotent stem cells from mesenchymal stromal cells derived from human third molars (wisdom teeth) by retroviral transduction of OCT3/4, SOX2, and KLF4 without MYC which is considered as oncogene. [J Biol Chem]

Bone Marrow Stromal Cells from Multiple Myeloma Patients Uniquely Induce Bortezomib Resistant NF-KappaB Activity in Myeloma Cells
Here researchers report that bone marrow stromal cells specifically derived from multiple myeloma (MM) patients are capable of further activating bortezomib-resistant NF-kappaB activity in MM cells. [Mol Cancer]

Adipose Tissue and Wharton’s Jelly Derived Mesenchymal Stromal Cells Suppress Lymphocyte Responses by Secreting Leukemia Inhibitory Factor
In this study, researchers investigated the capacity of mesenchymal stromal cells derived from adipose tissue and Wharton’s jelly to modulate lymphocyte proliferation as well as their impact on regulatory T cells. [Tissue Eng Part A]

Growth and Differentiation Properties of Mesenchymal Stromal Cell Populations Derived from Whole Human Umbilical Cord
Cells isolated from whole human umbilical cord (UC) satisfies all requirements essential for the generation of stem cell banks containing permanently available cell material for applications in the field of regenerative medicine. Nevertheless, further studies are needed to improve and adjust the methods which are already employed for adult mesenchymal stem cell expansion and differentiation to specific properties and requirements of the primitive stem cells collected from UC. [Stem Cell Rev]

Human Embryonic Stem Cell-Derived CD34+ Cells Function as MSC Progenitor Cells
Here researchers demonstrate human embryonic stem cells-derived CD34+CD73- cells can serve as mesenchymal progenitor cells with the ability to differentiate into adipocytes, osteoblasts and chondrocytes. [Bone]

Transcriptional Regulation of Oct4 in Human Bone Marrow Mesenchymal Stem Cells
This study showed that Oct4 and Sox2 genes were expressed in undifferentiated bone marrow mesenchymal stem cells (BM-MSCs) and BM-MSCs on day 7 but not on days 14 and 21 following osteogenic induction. [Stem Cells Dev]

Adipose Tissue-Derived Stem Cells for Cell Therapy of Airway Allergic Diseases in Mouse
Researchers compared murine mesenchymal stem cells of BALB/c mice derived from bone marrow and adipose tissue with respect to proliferation potential, immunophenotype, and multilineage differentiation capacity. [Acta Histochem]


INDUSTRY NEWS

AlloCure Names Robert M. Brenner, M.D. Chief Executive Officer
AlloCure Inc., a biotechnology company pioneering the use of cell therapies for the treatment of kidney diseases, announced the appointment of Robert M. Brenner, M.D., as President and Chief Executive Officer. [AlloCure Inc. Press Release]


POLICY NEWS

Research Budgets Face Austerity in 2012
The National Institutes of Health and other life sciences and biomedical research funding agencies will need to trim their budgets for 2012, which are to be planned over the summer, to satisfy a White House that is now stressing deficit reduction and belt-tightening after two years of stimulus funding-boosted research budgets. [The Office of Management and Budget, United States]

The Reality of Human Stem Cell Research in Europe
A new report from the European Science Foundation examines the key scientific questions for human stem cell research in the context of the rapidly emerging field of regenerative medicine. [European Science Foundation, European Union]

AstraZeneca Loses Generic Drug Case versus EU A European Union (EU) court backed an EU antitrust decision against Anglo-Swedish drug maker AstraZeneca, lending weight to a regulatory crackdown on firms blocking cheaper drugs coming to market. [The General Court, European Union]

Strong Medicine for French Research The medical-research adviser to France’s president aims to shift power and money to universities. [National Research Agency, France]

Meeting of the National Advisory Council for Healthcare Research and Quality [Agency for Healthcare Research and Quality, United States]

Maryland Stem Cell Research Commission – Public Meeting Notice [Maryland Stem Cell Research Commission, United States]

Center for Scientific Review; Notice of Closed Meetings [National Institutes of Health, United States]

Science Board Advisory Committee; Notice of Meeting (Docket No. FDA-2010-N-0001) [Food and Drug Administration, United States]

Guidance for Industry: Adaptive Design Clinical Trials for Drugs and Biologics [Food and Drug Administration, United States]

Medical Devices; Availability of Safety and Effectiveness Summaries for Premarket Approval Applications (Docket Nos. FDA-2010-M-0068, FDA-2010-M-0078, FDA-2010-M-0063, FDA-2010-M-0135, FDA-2010-M-0158) [Food and Drug Administration, United States]


EVENTS

Worldwide Innovative Networking (WIN) Symposium in Personalized Cancer Medicine
July 7-9, 2010
Paris, France

Translational Cancer Medicine 2010 – USA
July 11-14, 2010
San Francisco, United State

2nd International Conference on Cellular and Molecular Bioengineering (ICCMB2)
August 2-4, 2010
Singapore City, Singapore

Select Biosciences 3rd Annual Stem Cells Europe Conference
August 24-25, 2010
Edinburgh, Scotland

Select Biosciences Inaugural Cellular Therapy Summit
August 24-25, 2010
Edinburgh, Scotland


United Kingdom National Stem Cell Network (UKNSCN) 3rd Annual Scientific Conference
July 12-14, 2010
Nottingham, United Kingdom

Tissue Engineering & Regenerative Medicine International Society (TERMIS) – Asia Pacific 2010
September 15-17, 2010
Sydney, Australia

5th World Congress on Preventative and Regenerative Medicine (WCRM) 2010
October 5-7, 2010
Hannover, Germany

2010 American Society for Matrix Biology (ASMB) Meeting
October 24-27, 2010
Charleston, United States

52nd American Society of Hematology (ASH) Annual Meeting and Exposition
December 4-7, 2010
Orlando, United States

Tissue Engineering & Regenerative Medicine International Society (TERMIS) – North America 2010 Annual Conference
December 5-8, 2010
Orlando, United States

Visit our events page to stay up to date with the latest events in the cell, gene and immunotherapy community.

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