Volume 2.37 | Sep 21

Mesenchymal Cell News 2.37, September 21, 2010.
In this issue: Science News  |  Current Publications  |  Industry News  |  Policy News  |  Events Subscribe  |  Unsubscribe

TOP STORY

Keratinocyte Proximity and Contact Can Play a Significant Role in Determining Mesenchymal Stem Cell Fate in Human Tissue
Researchers show how the epidermal keratinocyte can direct human mesenchymal stem cell differentiation selectively. [FASEB J]

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SCIENCE NEWS

Fat Stem Cells Safe for Breast Reconstruction when Cancer is Dormant, Says Pitt Team
Fat-derived stem cells can be safely used to aid reconstruction of breast tissue after mastectomy as long as there is no evidence of active cancer, according to researchers. [Press release from the University of Pittsburgh Schools of the Health Sciences discussing online prepublication in Tissue Engineering Part A]

Ovary Stem Cell Treatment Could ‘Help Early Menopause Women’
Researchers in Cairo, Egypt, have come up with a way of restoring the ability of ovaries to produce eggs using cells developed in the lab. [International Federation of Gynecology and Obstetrics Press Release]

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CURRENT PUBLICATIONS (Ranked by Impact Factor of the Journal)

The Growth of Brain Tumors can be Suppressed by Multiple Transplantation of Mesenchymal Stem Cells Expressing Cytosine Deaminase
Here, researchers showed a potential ex vivo therapy that used mesenchymal stem cells as cellular vehicles to deliver a bacterial suicide gene, cytosine deaminase to brain tumors. [Int J Cancer]

Polyhydroxybutyrate and its Copolymer with Polyhydroxyvalerate as Biomaterials: Influence on Progression of Stem Cell Cycle
This study investigated the influence biomaterials, poly(3-hydroxybutyrate) and poly(3-hydroxybutyrate-co-3-hydroxyvalerate), exerted on cell cycle progression of olfactory ensheathing cells and mesenchymal stem cells commonly used in the engineering of nerve and bone tissues. [Biomacromolecules]

Low Doses of BMP4 Increases the Survival of Human Adipose-Derived Stem Cells Maintaining their Stemness and Multipotency
The results support BMP4 as a promising factor for expanding human adipose tissue-derived mesenchymal stem cells while maintaining their properties of stemness and multipotency. [Stem Cells Dev]

Inflammatory Conditions Affect Gene Expression and Function of Human Adipose Tissue-Derived Mesenchymal Stem Cells
Adipose tissue-derived mesenchymal stem cells were cultured with alloactivated peripheral blood mononuclear cells (mixed lymphocyte reaction), with proinflammatory cytokines [interferon (IFN)-gamma, tumour necrosis factor (TNF)-alpha and interleukin (IL)-6] or under control conditions, and their full genome expression and function examined. [ Clin Exp Immunol]

Myogenic Lineage Differentiated Mesenchymal Stem Cells Enhance Recovery from Dextran Sulfate Sodium-Induced Colitis in the Rat
Researchers investigated the role of transplanted mesenchymal stem cells in the repair phase of dextran sulfate sodium-induced colitis. [J Gastroenterol]

Zinc Supplementation Results in Improved Therapeutic Potential of Bone Marrow-Derived Mesenchymal Stromal Cells in a Mouse Ischemic Limb Model
Researchers wanted to determine whether zinc supplementation can inhibit bone marrow-derived mesenchymal stromal cell apoptosis and enhance their tissue regenerative potential in a mouse ischemic hindlimb model. [Cytotherapy]

Optimization of Culture Conditions for Osteogenically-Induced Mesenchymal Stem Cells in Beta-Tricalcium Phosphate Ceramics with Large Interconnected Channels
The aim of this study was to optimize culture conditions for human mesenchymal stem cells in beta-tricalcium phosphate ceramics with large interconnected channels. [J Tissue Eng Regen Med]


INDUSTRY NEWS

Mesoblast Featured at International Scientific Conferences
Clinical advances by regenerative medicine company Mesoblast Limited were featured prominently at the 39th annual meeting of the International Society for Experimental Hematology (ISEH) and the Tissue Engineering and Regenerative Medicine International Society (TERMIS) Asia Pacific meeting. [Mesoblast Limited Press Release]


POLICY NEWS

NHGRI Funds Development of Third Generation DNA Sequencing Technologies
More than $18 million in grants to spur the development of a third generation of DNA sequencing technologies was announced by the National Human Genome Research Institute. [National Institutes of Health, United States]

Innovative Emerging Molecular Analysis Technologies (SBIR R43/R44) (RFA-CA-10-013) [National Institutes of Health, United States]

Prospective Grant of Exclusive License: The Development of Immunotoxins/Targeted Toxins for the Treatment of Human Cancer (FR Doc. 2010-22844) [National Institutes of Health, United States]

National Human Genome Research Institute; Notice of Closed Meeting (FR Doc. 2010-23027) [National Institutes of Health, United States]

National Cancer Institute; Notice of Closed Meeting (FR Doc. 2010-23144) [National Institutes of Health, United States]

Center for Scientific Review; Notice of Closed Meetings (FR Doc. 2010-23143) [National Institutes of Health, United States]

Center for Scientific Review; Notice of Closed Meetings (FR Doc. 2010-23275) [National Institutes of Health, United States]

Agenda for the Public Workshop on Cell and Gene Therapy Clinical Trials in Pediatric Populations [Food and Drug Administration, United States]


EVENTS (Listed by Date)

2010 World Stem Cell Summit
October 4-6, 2010
Detroit, United States

5th World Congress on Preventative and Regenerative Medicine (WCRM) 2010
October 5-7, 2010
Hannover, Germany

17th Annual Meeting German Society for Gene Therapy (DG-GT e.V.)
October 6-9, 2010
Munich, Germany

bone-tec 2010 – International Bone-Tissue Engineering Congress
October 7-10, 2010
Hannover, Germany

NEW Functional Stem Cell and Regeneration
October 9-10, 2010
Kansas City, United States

The NYSCF Fifth Annual Translational Stem Cell Research Conference
October 12-13, 2010
New York, United States

NEW 4th International Symposium Stem Cells, Development and Regulation
October 12-14, 2010
Amsterdam, Netherlands

International Federation of Adipose Therapeutics & Science (IFATS) 2010 Conference
October 22-24, 2010
Dallas, United States

2010 American Society for Matrix Biology (ASMB) Meeting
October 24-27, 2010
Charleston, United States

NEW FDA Public Workshop on Cell and Gene Therapy Clinical Trials in Pediatric Populations
November 2, 2010
North Bethesda, United States

Stem Cell Society Singapore Symposium 2010
November 2-3, 2010
Singapore

NEW Select Biosciences 2nd International Forum on Stem Cells (2010 IFSC)
November 12-13, 2010
Tianjin, China

NEW The 16th International Conference of the International Society of Differentiation: From Stem Cells to Organisms
November 15-18, 2010
Nara, Japan

NEW Stem Cell Network’s 10th Annual Scientific Meeting
November 22-24, 2010
Calgary, Alberta

52nd American Society of Hematology (ASH) Annual Meeting and Exposition
December 4-7, 2010
Orlando, United States

Tissue Engineering & Regenerative Medicine International Society (TERMIS) – North America 2010 Annual Conference
December 5-8, 2010
Orlando, United States

Epithelial Plasticity and Epithelial to Mesenchymal Transition (A8)
January 21-26, 2011
Vancouver, Canada

Phacilitate 7th Annual Cell & Gene Therapy Forum 2011
January 24-26, 2011
Washington DC, United States

Stem Cells in Development, Tissue Homeostasis and Disease
January 30-February 4, 2011
Santa Fe, United States

NEW American Association for Cancer Research (AACR) Stem Cells, Development, and Cancer
March 3-6, 2011
Vancouver, Canada

Stem Cells, Cancer and Metastasis (C4)
March 6-11, 2011
Keystone, United States

Tissue Engineering & Regenerative Medicine International Society (TERMIS) – Europe 2010 Annual Conference
June 7-10, 2011
Granada, Spain

NEW International Society for Stem Cell Research (ISSCR) 9th Annual Meeting
June 15-18, 2011
Toronto, Canada

Visit our events page to stay up to date with the latest events in the cell, gene and immunotherapy community.



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