Volume 4.06 | Feb 14

Mesenchymal Cell News 4.06, February 14, 2012
     In this issue: Publications Industry News | Policy News | Events | Jobs 
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Increased Potency of Cardiac Stem Cells Compared with Bone Marrow Mesenchymal Stem Cells in Cardiac Repair
Researchers compared intramyocardial injection of human fetal cardiac-derived c-kit+ stem cells with two doses of adult mesenchymal stem cells or control (phosphate buffered saline) in nonobese diabetic/severe combined immune deficiency mice after coronary artery ligation. [Stem Cells Transl Med]
Abstract | Press Release

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PUBLICATIONS (Ranked by Impact Factor of the Journal)

Bone Marrow-Derived Human Mesenchymal Stem Cells Express Cardiomyogenic Proteins but Do Not Exhibit Functional Cardiomyogenic Differentiation Potential
To systematically evaluate the role of differentiation in mesenchymal stem cell (MSC)-mediated cardiac regeneration, the cardiomyogenic differentiation potential of human MSCs and murine MSCs was investigated in vitro and in vivo by inducing cardiomyogenic and non-cardiomyogenic differentiation. [Stem Cells Dev] Abstract

Primary Involvement of NADPH Oxidase 4 in Hypoxia-Induced Generation of Reactive Oxygen Species in Adipose-Derived Stem Cells
Researchers sought to investigate which subtype of NADPH oxidase (Nox) is primarily expressed in adipose-derived stem cells (ASCs), where Nox4 is localized in ASCs and whether silencing of Nox4 attenuates hypoxia-enhanced function of ASC. [Stem Cells Dev] Abstract

Mesenchymal Stem Cell-Conditioned Media Recovers Lung Fibroblasts from Cigarette Smoke-Induced Damage
In this study researchers attempted to determine whether mesenchymal stem cell-conditioned media can recover lung fibroblasts from cigarette smoke-induced damage. [Am J Physiol Lung Cell Mol Physiol] Abstract

Mesenchymal Stromal Cells Improve the Osteogenic Capabilities of Mineralized Agarose Gels in a Rat Full-Thickness Cranial Defect Model
Mesenchymal stromal cells (MSCs) have osteogenic potential and are considered useful for bone tissue engineering. The purpose of this study was to clarify the osteogenic abilities of MSCs loaded in HAp or CaCO3 gels using a rat cranial defect model compared to HAp and CaCO3 gels alone. [J Tissue Eng Regen Med] Abstract

Bone Tissue Engineering using Bone Marrow Stromal Cells and an Injectable Sodium Alginate/Gelatin Scaffold
Researchers investigate the potential application of bone marrow stromal cells and an injectable sodium alginate/gelatin scaffold for bone tissue engineering. [J Biomed Mater Res A] Abstract

Canine Bone Marrow Mesenchymal Stromal Cells with Lentiviral mHCN4 Gene Transfer Create Cardiac Pacemakers
Researchers’ aim was to test the ability of canine mesenchymal stromal cells transfected with the mouse hyperpolarization-activated cyclic nucleotide-gated channel 4 (mHCN4) gene to deliver a biologic pacemaker to the canine heart. [Cytotherapy] Abstract

Basic Fibroblast Growth Factor Modulates Cell Cycle of Human Umbilical Cord-Derived Mesenchymal Stem Cell
This study has aimed to establish optimum conditions to generate and characterize mesenchymal stem cells (MSC) from human umbilical cord. [Cell Prolif] Abstract

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Mesenchymal Stem Cells Have New Cell Culture Environment
BD Biosciences announced the availability of the new BD Mosaic™ Mesenchymal Stem Cell Serum-Free, a complete cell culture environment for human mesenchymal stem cells derived from bone marrow. [BD Biosciences] Press Release

American CryoStem Joins Alliance for Regenerative Medicine
American CryoStem Corporation, a commercial developer, manufacturer and marketer of clinical products and services involving adipose tissue and adipose derived adult stem cells, announced its association with the Alliance for Regenerative Medicine. [American CryoStem Corporation] Press Release


National Institutes of Health (United States)

Food and Drug Administration (United States)

Center for Biologics Evaluation and Research (United States)

European Medicines Agency (European Union)

Medicines and Healthcare Products Regulatory Agency (United Kingdom)

Therapeutic Goods Administration (Australia)


NEW Harvard Stem Cell Institute (HSCI) Stem Cell Salon: Mesenchymal Stem Cells in Clinical Trial
March 12, 2012
Boston, United States

NEW Forum of Italian Researchers on Mesenchymal and Stromal Stem Cells (FIRST): 4th Annual Meeting
May 14, 2012
Pavia, Italy

Visit our events page to see a complete list of events in the mesenchymal cell community.


Research and Development Technologist, hPSC Media (STEMCELL Technologies)

Scientist – Pluripotent Stem Cells (STEMCELL Technologies)

Scientific Marketing Communications Specialist (STEMCELL Technologies)

Research Technologist, Manufacturing Sciences (STEMCELL Technologies)

Business Analyst – Product Management (STEMSOFT Software)

Research Associates/Scientist/Senior Scientist – Stem Cell Research (Advanced Cell Technology) 

PhD Student – Immunotherapy Using Mesenchymal Stem Cells (Charles University)

Postdoctoral Position – Molecular Cell Biology (Weizmann Institute of Science) 

Postdoctoral Fellow (University of Rochester Medical Center)

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