Mesenchymal Stromal Cells in Renal Transplantation: Opportunities and Challenges|
Bone marrow-derived multipotent mesenchymal stromal cells have emerged as a potential candidate for cell-based therapy to modulate the immune response in organ transplantation. These cells can repair tissue after injury and downregulate many of the effector functions of immune cells that participate in the alloimmune response, converting them into regulatory cells. [Nat Rev Nephrol] Abstract
Mesenchymal Stem Cell-Based Therapy in Kidney Transplantation
The authors summarize the findings of a large number of studies and aim to provide an objective viewpoint based on a comprehensive analysis of the presently established benefits and obstacles of implementing mesenchymal stem cell-based therapy in kidney transplantation, and promote its clinical translation. [Stem Cell Res Ther] Full Article
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